N33-TEG-COOH (N3-TEG-COOH)

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100mg

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855.00

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N33-TEG-COOH是一种PROTAC连接桥，含有四个聚乙二醇(PEG)单元。详细信息请看参考文献PMID:26035625中的Compound7。

货号：ajce50152
CAS：201467-81-4
分子式：C10H19N3O6
分子量：277.27
纯度：98%
存储：Store at -20°C
库存：现货

Background:

N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.

N33-TEG-COOH is a long linker extracted from Reference PMID: 26035625, Compound 7. A PROTAC is a heterobifunctional compound that contains two ligands connected by a linker unit. One ligand binds an E3 ubiquitin ligase protein, while the other ligand binds to the target protein of interest, thereby bringing the ligase and the target in close proximity[1].

[1]. Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.