全部分类
  • F1063-0967
F1063-0967的可视化放大

F1063-0967

A DUSP26 inhibitor

此产品仅用于科学研究,我们不为任何个人用途提供产品和服务

F1063-0967的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 5mg
    ¥600.00
    480.00
    - +
  • 10mg
    ¥987.00
    790.00
    - +
  • 50mg
    ¥2725.00
    2180.00
    - +
  • 100mg
    ¥3775.00
    3020.00
    - +
已选 0 0
金额: ¥0.00
首页 收藏
  • 货号: ajce50696
  • CAS: 613225-56-2
  • 别名:
  • 分子式: C24H24N2O5S2
  • 分子量: 484.59
  • 纯度: >98%
  • 溶解度: DMSO : 125 mg/mL (257.95 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

F1063-0967 is an inhibitor of dual-specificity phosphatase 26 (DUSP26; IC50 = 11.62 ?M).1 It induces IMR-32 neuroblastoma cell apoptosis (IC50 = 4.13 ?M).


1.Ren, J.-X., Cheng, Z., Huang, Y.-X., et al.Identification of novel dual-specificity phosphatase 26 inhibitors by a hybrid virtual screening approach based on pharmacophore and molecular dockingBiomed. Pharmacother.89376-385(2017)

Protocol

Cell experiment:

The IMR-32 cells are plated in 96-well plates with 1×103 cells per well. After the cells are allowed to settle for 24 h, F1063-0967 (0, 10, 1, and 0.1 μM) is added. An MTTassay is performed. For cell lines HL7702 and SH-SY5Y, the cells are allowed to settle for 24 h, F1063-0967 (10 μM) is added, then MTT assays are carried out after 72 h[1].

参考文献:

[1]. Ren JX, et al. Identification of novel dual-specificity phosphatase 26 inhibitors by a hybrid virtual screening approach based on pharmacophore and molecular docking. Biomed Pharmacother. 2017 May;89:376-385.

没有评价数据

温馨提示 ×
商品已成功加入购物车!
购物车共 0 件商品
去购物车结算