CHK-IN-1是一种CHK1和CHK2的抑制剂,具有抗增殖作用。
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CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.
CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].
[1]. Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1
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