Vebufloxacin (Flumenique)

Vebufloxacin (Flumenique) (Flumenique; OPC7241; DM8966) 对革兰氏阳性和阴性细菌具有有效的抗菌活性。

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库存: 现货

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促销价

数量
1mg

￥6200.00

4960.00

- +
5mg

￥12175.00

9740.00

- +
10mg

￥20762.00

16610.00

- +
20mg

￥36562.00

29250.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Vebufloxacin (Flumenique; OPC7241; DM8966) exhibits potent antibacterial activity against gram-positive and -negative bacteria.

A series of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids is synthesized and tested for antibacterial activities. Among them, Vebufloxacin (OPC-7241) exhibits potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa, and OPC-7251 shows potent activity characteristically against Propionibacterium acnes[1].

[1]. Ishikawa H, et al. Studies on antibacterial agents. I. Synthesis of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids. Chem Pharm Bull (Tokyo). 1989 Aug;37(8):2103-8.