3',4'-Dihydroxyflavonol

3',4'-Dihydroxyflavonol(DiOHF)是一种有效的抗氧化剂，可降低糖尿病大鼠肠系膜动脉中的超氧化物并改善NO功能。

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库存: 现货

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5mg

￥762.00

610.00

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10mg

￥1300.00

1040.00

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25mg

￥2825.00

2260.00

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50mg

￥4425.00

3540.00

- +

已选 0 种 0 瓶

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Background

3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1].

3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function[1].3',4'-Dihydroxyflavonol reduces vascular contraction through Ca2? desensitization in permeabilized third-order branches of rat mesenteric arteries[2].

[1]. Leo CH, et al. 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One. 2011;6(6):e20813. [2]. Kim HY, et al. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca2? desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):191-202.