Axltide 是基于小鼠胰岛素受体的底物1 (氨基酸 979-989)。Axltide 是 Axl、DDR2、Mst1和JAK2激酶的底物。
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Axltide is based on the mouse Insulin receptor substrate 1 (amino acid 979-989). Axltide is a substrate for Axl, DDR2, Mst1, and JAK2 kinases[1].
[1]. Wang H, et al. Cellular chromium enhances activation of insulin receptor kinase. Biochemistry. 2005 Jun 7;44(22):8167-75.
Peficitinb (ASP015K, JNJ-54781532)
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