BAY-678 racemate

BAY-678 racemate 是 BAY-678 的消旋体。BAY-678 是具有口服生物活性的、高效的、选择性的、人中性粒细胞弹性蛋白酶(HNE) 的细胞渗透性抑制剂，其 IC50 值为 20 nM。BAY-678 也是被基因结构组学联盟 (SGC) 推荐的化学探针。

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥1212.00

970.00

- +
10mg

￥2012.00

1610.00

- +
25mg

￥4037.00

3230.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajce55194
CAS: 675103-35-2
别名:
分子式: C20H15F3N4O2
分子量: 400.35
纯度: >98%
溶解度: DMSO: ≥ 150 mg/mL (374.67 mM); Water: < 0.1 mg/mL (insoluble)
储存: Store at -20°C
库存: 现货

Background

BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

[1]. von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.