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  • Bruceine D
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Bruceine D

Bruceine D, isolated from Brucea javanica (L.) Merr. (Simaroubaceae), shows antineoplastic properties in various human cancers including pancreas, breast, lung, blood, bone, and liver. Bruceine D induces apoptosis in human chronic myeloid leukemia K562 ce

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  • 货号: ajce55360
  • CAS: 21499-66-1
  • 别名: 鸦胆子苦素D
  • 分子式: C20H26O9
  • 分子量: 410.42
  • 纯度: >98%
  • 溶解度: DMSO: 100 mg/mL (243.65 mM)
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

Bruceine D, isolated from Brucea javanica (L.) Merr. (Simaroubaceae), shows antineoplastic properties in various human cancers including pancreas, breast, lung, blood, bone, and liver. Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway.


[1] Jian-Ye Zhang, et al. Am J Cancer Res . 2016 Mar 15;6(4):819-26. [2]Zi Wayne Sin, et al. Explor Target Antitumor Ther. 2020;1:200–217

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