Desoximetasone

A glucocorticoid

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
10mg

￥650.00

520.00

- +
50mg

￥1962.00

1570.00

- +
100mg

￥0.00

0.00

- +
200mg

￥0.00

0.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajce55930
CAS: 382-67-2
别名: 去羟米松
分子式: C22H29FO4
分子量: 376.46
纯度: >98%
溶解度: DMSO: ≥ 100 mg/mL (265.63 mM); Water: 0.14 mg/mL (0.37 mM)
储存: Store at -20°C
库存: 现货

Background

Desoximetasone is a glucocorticoid.¹ In vivo, desoximetasone (0.001-0.1 mg) reverses increases in epidermal cell proliferation induced by phorbol 12-myristate 13-acetate in SENCAR mice when administered topically. It also reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice, indicating anti-inflammatory action. Formulations containing desoximetasone have been used in the treatment of psoriasis and atopic dermatitis.

1.Kowalczyk, P., Junco, J.J., Kowalczyk, M.C., et al.The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR miceMol. Carcinog.53(6)488-497(2014)