Isorosmanol

Isorosmanol 是从鼠尾草叶中分离出的一种松香烷型二萜，具有抗氧化、神经保护和神经营养作用。Isorosmanol 能抑制 AChE 活性和黑色素的合成。

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Background

Isorosmanol is an abietane-type diterpene isolated from the leaves of sage, with antioxidant, neuroprotective and neurotrophic effects. Isorosmanol inhibits AChE activity and melanin synthesis[1][2][3].

[1]. Miura K, et al. Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method. J Agric Food Chem. 2002 Mar 27;50(7):1845-51. [2]. Park SY, et al. Neuroprotective and neurotrophic effects of isorosmanol. Z Naturforsch C. 2009 May-Jun;64(5-6):395-8. [3]. Sallam A, et al. Acetylcholine esterase inhibitors and melanin synthesis inhibitors from Salvia officinalis. Phytomedicine. 2016 Sep 15;23(10):1005-11.