Mirodenafil

A PDE5 inhibitor

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

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包装

价格

促销价

数量
5mg

￥425.00

340.00

- +
10mg

￥675.00

540.00

- +
50mg

￥2025.00

1620.00

- +
100mg

￥3237.00

2590.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Mirodenafil is a phosphodiesterase 5 (PDE5) inhibitor.¹ It increases penile intracavernosal pressure (ICP) in a rat model of diabetes induced by streptozotocin and in a rat model of cavernosal nerve injury when administered at doses of 1 and 10 mg/kg, respectively.^1,2 Mirodenafil (4 mg/kg per day) decreases bladder wall submucosal fibrosis and degeneration in a rat model of chronic bladder ischemia.³ It also decreases bladder overactivity in a female rat model of partial bladder outlet obstruction.⁴

1.Park, K., Cho, S.Y., and Kim, S.W.Erectile response to type 5 phosphodiesterase inhibitor could be preserved with the addition of simvastatin to conventional insulin treatment in rat model of diabetesInt. J. Androl.34(5 Pt 2)e468-e474(2011) 2.Kim, H., Sohn, D.W., Kim, S.D., et al.The effect of mirodenafil on the penile erection and corpus cavernosum in the rat model of cavernosal nerve injuryInt. J. Impot. Res.22(5)291-297(2010) 3.Choi, H., Bae, J.H., Shim, J.S., et al.Mirodenafil prevents bladder dysfunction induced by chronic bladder ischemia in ratsInt. Neurourol. J.19(1)19-26(2015) 4.Kang, J.Y., Kim, E.K., and Kim, K.M.Effects of mirodenafil, a phosphodiesterase-5 inhibitor, on female rat bladder in a partial bladder outlet obstruction model: Physiological and immunohistochemical aspectsKorean J. Urol.54(5)339-344(2013)