Praziquantel D11

An internal standard for the quantification of praziquantel

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库存: 现货

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1mg

￥1300.00

1040.00

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5mg

￥4850.00

3880.00

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10mg

￥8637.00

6910.00

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货号: ajce58158
CAS: 1246343-36-1
别名: 吡喹酮 D11
分子式: C19H13D11N2O2
分子量: 323.47
纯度: >98%
溶解度: Chloroform: soluble,Methanol: soluble
储存: Store at -20°C
库存: 现货

Background

Praziquantel-d₁₁ is intended for use as an internal standard for the quantification of praziquantel by GC- or LC-MS. Praziquantel is an anthelmintic agent.^1,2 It is lethal to S. mansoni schistosomula and adults (LC₅₀s = 0.68 and 0.03 mg/ml, respectively).² Praziquantel (172 and 592 mg/kg) reduces worm burden in a mouse model of S. mansoni infection. Formulations containing praziquantel have been used in the treatment of schistosomiasis.

1.Cook, G.C.Anthelminthic agents: Some recent developments and their clinical applicationPostgrad. Med. J.67(783)16-22(1991) 2.Olliaro, P., Delgado-Romero, P., and Keiser, J.The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer)J. Antimicrob. Chemother.69(4)863-870(2014)