Peiminine

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20mg

￥1985.00

1786.00

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Extracted from Fritillaria;Store the product in sealed,cool and dry condition

货号：ajcn4410
CAS：18059-10-4
分子式：C27H43NO3
分子量：429.63
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.IC50 value:Target:Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.

参考文献:
[1]. Guo H, et al. Peiminine ameliorates bleomycin-induced acute lung injury in rats. Mol Med Rep. 2013 Apr;7(4):1103-10.