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Background:
Triptophenolide is a colorless crystalline plate isolated from ethyl acetate extracts of Tripterygium wilfordii. IC50 value:Target:In vitro: Triptophenolide can remarkably inhibit the delayed type hypersensitivity (DTH) reaction induced by DNCB and BSA; and diminished the peripheral blood ANAE+lymphocytes in rats and micc. Moreover, triptophenolide can dramatically increase the amount of total serum complement and significautly decrcase the serum antibody products (1gG ) of rats and mice. The phagocytosis of perioneal exudate macrophages in mice present double effects in vitro [1].In vivo:
参考文献:
[1]. XU bin, et al. Study on polarographic catalytic wave of triptophenolide. Chinese Journal of Analysis Laboratory, 2005-04
[2]. Yang Jun, et al. Studies on Antiinflammatory and Immune Effects of Triptophenolide. Chinese Traditional and Herbal Drugs, 1995-01
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