N－Methylcytisine

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20mg

￥4494.00

4044.00

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Extracted?from?Sophora flavescens Ait dried roots;Store?the?product?in?sealed,?cool?and?dry?condition

货号：ajcn4864
CAS：486-86-2
分子式：C12H16N2O
分子量：204.27
纯度：98%
存储：Store at -20°C
库存：现货

Background:

N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system and has a high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia[1][2].

参考文献:
[1]. Jiao YF, et al. N-Methylcytisine Ameliorates Dextran-Sulfate-Sodium-Induced Colitis in Mice by Inhibiting the Inflammatory Response. Molecules. 2018 Feb 25;23(3). pii: E510.
[2]. Pliashkevich IuG, et al. [N-methylcytisine--a selective ligand of nicotinic receptors of acetylcholine in the CNS]. Biull Eksp Biol Med. 1987 Dec;104(12):690-2.