2-(2-Methylbenzamido)acetic acid-d7 是 2-(2-Methylbenzamido)acetic acid 的氘代物。2-(2-Methylbenzamido)acetic acid 为一种代谢物,可以在尿液中检测到。
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2-(2-Metlbenzamido)acetic acid-d7 is the deuterium labeled 2-(2-Metlbenzamido)acetic acid. 2-(2-Metlbenzamido)acetic acid is a metabolite detected in urine.
Stable heavy isotopes of drogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Remane D, et al. Validation of a multi-analyte HPLC-DAD method for determination of uric acid, creatinine, homovanillic acid, niacinamide, hippuric acid, indole-3-acetic acid and 2-metlhippuric acid in human urine. J Chromatogr B Analyt Technol Biomed L
DMNPE-caged ATP diammonium salt
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