5α-Hydroxycostic acid

5α-Hydroxycostic acid 是一种从草药 Laggera alata 中分离出的桉烷型倍半萜烯。5α-Hydroxycostic acid 通过调节 VEGF/VEGFR2 和 Ang2/Tie2 途径通过调节抑制血管生成并抑制乳腺癌细胞迁移。

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库存: 现货

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5mg

￥6362.00

5090.00

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Background

5α-droxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-droxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways^[1].

[1]. Liang N, et, al. Two natural eudesmane-type sesquiterpenes from Laggera alata inhibit angiogenesis and suppress breast cancer cell migration through VEGF- and Angiopoietin 2-mediated signaling pathways. Int J Oncol. 2017 Jul;51(1):213-222.