Background
Mca-KPLGL-Dap(Dnp)-AR-NH2 is a fluorogenic substrate for matrix metalloproteinases (MMPs).1 Upon cleavage by MMPs, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.
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