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DNA31
DNA31 是囊性纤维化跨膜传导调节因子 (CFTR) 基因的全球最常见的 31 种突变。DNA31 用于针对囊性纤维化 (CF) 的新生儿筛查方案的第一级遗传测试。
Bafilomycin C1
A fungal metabolite with diverse biological activities
VX-661
An investigational compound that promotes the maturation of delta F508 CFTR
Lubiprostone
A ClC-2 activator
CFTRinh-172
A potent CFTR channel blocker
Remimazolam
CGP 36742
A GABAB receptor antagonist
Acamprosate calcium
An NMDA modulator
CFTR corrector 2
FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.
Elacridar hydrochloride
An inhibitor of MRP-1 and BCRP
(R)-Baclofen hydrochloride
A GABAB receptor agonist
Ko 143
Inhibitor of the multidrug transporter BCRP
Transdermal Peptide (TD 1 (peptide))
Transdermal Peptide(TD 1(肽))由11个氨基酸组成,是第一个通过噬菌体展示发现的透皮增强肽。
CAY10719
A selective inhibitor of ABCG2
Dynorphin A 1-10
Dynorphin A (1-10) 是一种内源性的阿片样神经肽,与 κ 阿片受体 (κ-opioid receptor) 结合。Dynorphin A (1-10) 也阻断 NMDA 激活的电流,IC50 为 42.0 μM。