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NP-12
A PL-1/PD-L interaction inhibitor
Atezolizumab (MPDL3280A)
Atezolizumab (MPDL3280A) (MPDL3280A) 是一种针对程序性死亡配体 1 (PD-L1) 的选择性人源化单克隆 IgG1 抗体,用于癌症研究。
Dapansutrile
An NLRP3 inflammasome inhibitor
IRAK-1-4 Inhibitor I
A benzimidazole
Leukadherin 1
An allosteric activator of CD11b/CD18
TNP
An IP6K and IP3K inhibitor
BEC
An inhibitor of arginase types I and II
L-NIL
A selective iNOS inhibitor
4'-Methoxyresveratrol
A stilbene with diverse biological activities
Benzoylgomisin O
Benzoylgomisin O 是从 Schisandra rubriflora 中分离的化合物,对 15-LOX、COX-1、COX-2 酶有抑制作用,且具有抗炎活性。
Polymyxin B nonapeptide
Polymyxin B nonapeptide, as a cationic cyclic peptide derived from polymyxin B, can increase the permeability of the outer membrane (OM) of GNB toward hydrophobic antibiotics probably.
GNF351
GNF351 is a potent antagonist of aryl hydrocarbon receptor (AHR). GNF351 interacts directly with the AHR ligand binding pocket and competes with a well-characterized photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM.
5-methyl Chrysene
An aryl hydrocarbon receptor agonist
Propyphenazone (4-Isopropylantipyrine)
Propyphenazone(4-Isopropylantipyrine, Isopropyrine), an analgesic and antipyretic agent, is a selective cyclooxygenase-2 inhibitor with anti-inflammatory activity.
Mivotilate (YH439)
Mivotilate (YH439) 是一种无毒、有效的芳烃受体 (AhR) 激活剂,可作为保肝剂。