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PDE4B Inhibitor
A PDE4B inhibitor
Bengamide B
Potent inhibitor of NF-κB activation
Withanone
A phytochemical with diverse biological activities
M04
A STING agonist
BMS 470539 (hydrochloride)
An MC1R agonist
TH 1020
An inhibitor of the TLR5-flagellin protein-protein interaction
Diprovocim-1
An agonist of TLR1/TLR2
T6167923
T6167923是一种有效的、选择性的 MyD88 依赖性信号通路抑制剂。T6167923 直接与 MyD88 的 Toll/IL1 受体 (TIR) 结构域结合,破坏 MyD88 的同二聚体形成。T6167923 抑制 NF-κB 驱动的葡萄球菌肠毒素AP (SEAP) 活性,并且改善抗炎活性,对 IFN-γ,IL-1β,IL-6 和 TNF-α 的 IC50 分别为 2.7 μM,2.9 μM,2.66 μM 和 2.66 μM。
FSL-1 (trifluoroacetate salt)
A neuropeptide with diverse biological activities
WKYMVM-NH2 TFA
WKYMVM-NH2 TFA 是有效的 N-甲酰肽受体 FPR1 和 FPRL1/2 的激动剂,同时可以激活一些白细胞效应功能,如趋化性、激活补体受体-3 及 NADPH 氧化酶。
Raloxifene-d4 (hydrochloride)
An internal standard for the quantification of raloxifene
YQ128
An NLRP3 inflammasome inhibitor
CU-115
A TLR8 antagonist
1V209
1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.
Metoprolol-d6 (tartrate)