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Arginase inhibitor 1
Durvalumab
Nivolumab (BMS-936558)
Nivolumab (BMS-936558) 是一种程序性死亡受体-1 (PD-1) 阻断人 IgG4 抗体,用于治疗晚期(转移性)非小细胞肺癌。
CB-1158 (INCB01158)
An arginase inhibitor
PF06650833
PF06650833 (PF-06650833) 是一种有效的、选择性的和口服活性的白细胞介素 1 受体相关激酶 4 (IRAK4) 抑制剂,在细胞和 PBMC 试验中的 IC50 分别为 0.2 和 2.4 nM。
MCC950 (CP-456773)
An inhibitor of NLRP3 inflammasome activation
JHU-083
JHU-083 (Ethyl 2-(2-Amino-4-methylpentanamido)-DON) is a novel prodrug of DON.JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.Solutions are best fre
FICZ
FICZ (Formyl-indolo [3,2-b] carbazole), as an endogenous ligand for the aryl hydrocarbon receptor (AhR).
β-Zearalenol
A hepatic metabolite of zearalenone
C3a Receptor Agonist
A C3a receptor agonist
CA-4948
An IRAK-4 inhibitor
Furimazine (PBI 3939)
Furimazine是一种咪唑并吡嗪酮类的发光底物。在哺乳动物细胞中,NanoLuc(Nluc)与Furimazine联用,产生更亮的发光,比带Coelenterazine的Oluc-19高250万倍。
PP121
A potent dual inhibitor of tyrosine and phosphoinositide kinases
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt 是D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3) 的六钾盐。是一种第二信使。可刺激钙从内质网排出。
nor-NOHA (acetate)
A potent arginase inhibitor