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Brevilin A
Isorhapontigenin
GNE0877
A selective LRRK2 inhibitor
EN6
An activator of autophagy
CZC-25146
A potent LRRK2 inhibitor
QX77
An activator of chaperone-mediated autophagy
JH-II-127
An inhibitor of wild-type and mutant forms of LRRK2
GNE-9605
PF-06447475
PF-06447475 是一种高效、选择性和脑渗透性 LRRK2 抑制剂,IC50 为 3 nM。
ERK5-IN-1
An ERK5 inhibitor
Pennogenin 3-O-beta-chacotrioside
Pennogenin 3-O-beta-chacotrioside, an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1, and posesses anti-colorectal cancer activity.
MLi-2
An LRRK2 inhibitor
NSC 185058
An inhibitor of ATG4B
3'-Hydroxypterostilbene
3'-Hydroxypterostilbene (3'-HPT) is one of the active constituents of Sphaerophysa salsula and Pterocarpus marsupium which may be useful in treating different types of haematological malignancies. 3'-Hydroxypterostilbene, a natural pterostilbene analogue,
GSK2578215A