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CFI-402257 hydrochloride
CFI-402257 hydrochloride是高度选选择性,具有口服活性的TTK/Mps1抑制剂,体外对TTK 的IC50值为1.7 nM。CFI-402257 hydrochloride 具有抗癌活性。
Mps1-IN-2
An inhibitor of Mps1
AZ3146
A selective inhibitor of the spindle checkpoint kinase Mps1
Mps1-IN-3
Mps1-IN-3 是一种有效的,选择性的 MPS1 抑制剂,IC50 值为 50 nM。
BOS-172722
BOS172722 is a monopolar spindle 1 (MPS1) checkpoint inhibitor with IC50 of 11 nM, Ki of 0.11 nM.
BAY1217389
An orally bioavailable inhibitor of Mps1
CFI-402257
CFI-402257是Mps1的选择性抑制剂,CFI-402227抑制Mps1,IC50值为1。
NMS-P715 analog
NMS-P715 analog is an inhibitor of MPS1, with an IC50 of 84 nM.
TC Mps1 12
TC Mps1 12 是一种有效的选择性单极纺锤体 1 (Mps1) 抑制剂,IC50 为 6.4 nM。
NMS-P715
An Mps1/TTK inhibitor
Empesertib (BAY 1161909)
Empesertib (BAY1161909, Mps1-IN-5), a derivative of triazolopyridine, is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase with IC50 of <1 nM. Empesertib has potential antineoplastic activity.
MPS1/TTK Inhibitor
An inhibitor of Mps1/TTK
Mps1-IN-1
A selective Mps1 kinase inhibitor
MPI-0479605
A potent inhibitor of MPS1
CCT251455
CCT251455是有效和选择性的有丝分裂激酶单极纺锤体1(MPS1)抑制剂,IC50值为3nM。