我的订单
商品收藏
没有相关数据
筛选出 272 条数据,请点击查看商品详情
Conteltinib
Conteltinib (CT-707) 是一种多激酶抑制剂,可靶向作用于 FAK,ALK 和 Pyk2。Conteltinib (CT-707) 对 FAK 具有显着的抑制作用,IC50 为 1.6 nM。
BIBF0775
BIBF-0775 is a selective inhibitor of transforming growth factor β Receptor I (TGFβRI,Alk5) with an IC50 of 34nM.
LDN193189 Tetrahydrochloride
An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6
F-1
F-1 是一种有效的 ALK 和 ROS1 的双重抑制剂,抑制 ALK 的磷酸化及下游通路,对 ALKWT,ROS1WT,ALKL1196M 和 ALKG1202R 的 IC50 值分别为 2.1 nM,2.3 nM,1.3 nM 和 3.9 nM。
Ensartinib hydrochloride (X-396 hydrochloride)
An ALK inhibitor
Vactosertib Hydrochloride
Vactosertib Hydrochloride (EW-7197 Hydrochloride) 是 TGFβRI (ALK5) 的小分子 ATP 竞争性抑制剂,其 IC50 值为 12.9 nM。
EML4-ALK kinase inhibitor 1
EML4-ALK kinase inhibitor 1 是有效的、具有口服活性的类棘皮细胞微管相关蛋白4-间变性淋巴瘤激酶 (EML4-ALK) 的抑制剂,其 IC50 值为 1 nM。
Repotrectinib
A multi-kinase inhibitor
JH-VIII-157-02
JH-VIII-157-02是alectinib的结构类似物,为ALK抑制剂,对棘皮动物微管相关蛋白样4(EML4)-ALKG1202R的IC50值为2nM。
ALK-IN-6
ALK-IN-6 (compound 11) 是口服有效的,间变性淋巴瘤激酶 (ALK) 的抑制剂,其对野生型 ALK、ALK F1196M 和ALK F1174L 的 IC50 值分别为 71 nM、18.72 nM 和36.81 nM。
ALK inhibitor 1
ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor which can inhibit testis-specific serine/threonine kinase (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM).
A 83-01
A TGF-β type I receptor inhibitor
Alectinib Hydrochloride
Alectinib (AF802, CH5424802, RO5424802, RG-7853) is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase.
R-268712
R-268712 is a potent and selective inhibitor of ALK5 with an IC50 of 2.5 nM.
LDN-193189